Rocky, absolutely no issues as long as you check a couple of things when you connect it. You said battery tender, do you mean the official battery maintainer from GM or the CTEK 3300 version (they manufacture it for GM) or similar unit that is a true chip controlled maintainer. Make sure that your connections are secure, that the maintainer is functioning correctly when you connect it (do it a day or so in advance to make sure it is cycling properly), and that you have it raised off the garage floor on some tiles or similar, so as to prevent any moisture from getting to it. Over the years I have had mine connected for up to 8 weeks without any issues.